Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 3/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18107448 | 1.00 | TSHR (0.50) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL18107414 | 1.00 | TSHR (0.50) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL18107286 | 1.00 | TSHR (0.50) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL8668923 | 1.00 | TSHR (0.50) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL18107222 | 1.00 | TSHR (0.50) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL18107312 | 1.00 | TSHR (0.50) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL18107205 | 0.98 | TSHR (0.48) | TSHRALDH1A1TDP1LMNADNM1 | |
| Ammonia Solution, Strong SCHEMBL8943044 | 0.98 | TSHR (0.48) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL18107229 | 0.98 | TSHR (0.48) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL18107320 | 0.98 | TSHR (0.48) | TSHRALDH1A1TDP1LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738738-B2 | Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group | BRIDGESTONE CORPORATION (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20160289355-A1 | POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP | BRIDGESTONE CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |