Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18112622 | 1.00 | PTPN1 (0.35) | PTPN1APPPTPN2PTPN6MEN1 | |
| SCHEMBL18112624 | 0.87 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL18112625 | 0.87 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL18118856 | 0.87 | HTRA1 (0.30) | MEN1KMT2A | |
| SCHEMBL18118795 | 0.85 | TRPV1 (0.33) | — | |
| SCHEMBL18118853 | 0.83 | — | — | |
| SCHEMBL2015655 | 0.80 | CA1 (0.35) | — | |
| SCHEMBL18118860 | 0.79 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL18118854 | 0.79 | KMT2A (0.34) | MEN1KMT2A | |
| SCHEMBL18112606 | 0.79 | BACE1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016155831-A1 | ISOXAZOLINE-STYRENE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |