Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113194 | 0.89 | TSHR (0.53) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18113097 | 0.86 | TSHR (0.50) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18113084 | 0.86 | TSHR (0.63) | TSHRALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL18113211 | 0.85 | TSHR (0.49) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18113303 | 0.84 | TSHR (0.48) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18113269 | 0.84 | TSHR (0.50) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18113159 | 0.83 | TSHR (0.65) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18113220 | 0.82 | TSHR (0.44) | TSHRALDH1A1HSD17B10LMNACASP3 | |
| SCHEMBL18113301 | 0.81 | TSHR (0.62) | TSHRALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL18113099 | 0.81 | TSHR (0.62) | TSHRALDH1A1HSD17B10LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428870-B | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限公司 | 2019-06-14 | — | — | CN | disclosed |
| EP-3277736-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| EP-3277736-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-02-07 | — | — | EP | disclosed |
| CN-107428870-A | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限公司 | 2017-12-01 | — | — | CN | disclosed |
| WO-2016156473-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-10-06 | — | — | WO | disclosed |