⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113991 | 0.89 | — | — | |
| SCHEMBL19999936 | 0.86 | — | — | |
| SCHEMBL19999929 | 0.81 | — | — | |
| SCHEMBL18114011 | 0.78 | — | — | |
| SCHEMBL18113998 | 0.76 | ACACB (0.33) | — | |
| SCHEMBL18059669 | 0.76 | — | — | |
| SCHEMBL16644682 | 0.76 | — | — | |
| SCHEMBL16637915 | 0.76 | — | — | |
| SCHEMBL16637916 | 0.76 | — | — | |
| Trifluoroacetic Acid SCHEMBL18113990 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277685-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | MUTABILIS (FR) | 2021-01-13 | — | — | EP | disclosed |
| US-10570131-B2 | Heterocyclic compounds and their use in preventing or treating bacterial infections | MUTABILIS (FR) | 2020-02-25 | — | — | US | disclosed |
| US-20180086760-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | MUTABILIS (FR) | 2018-03-29 | — | — | US | disclosed |
| EP-3277685-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | Mutabilis (FR) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016156344-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | MUTABILIS (FR) | 2016-10-06 | — | — | WO | disclosed |
| WO-2016156346-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | MUTABILIS (FR) | 2016-10-06 | — | — | WO | disclosed |