Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 9/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoxaflutole SCHEMBL21645075 | 0.89 | DHODH (0.48) | DHODHCACNA1BNR1I2MEN1KMT2A | |
| Isoxaflutole SCHEMBL66989 | 0.89 | DHODH (0.48) | DHODHCACNA1BNR1I2MEN1KMT2A | |
| Isoxaflutole SCHEMBL29355326 | 0.89 | DHODH (0.48) | DHODHCACNA1BNR1I2MEN1KMT2A | |
| Isoxaflutole SCHEMBL20723459 | 0.88 | DHODH (0.47) | DHODHCACNA1BNR1I2MEN1KMT2A | |
| Isoxaflutole SCHEMBL20723475 | 0.88 | DHODH (0.47) | DHODHCACNA1BNR1I2MEN1KMT2A | |
| Isoxaflutole SCHEMBL28263023 | 0.87 | DHODH (0.47) | DHODHCACNA1BNR1I2MEN1KMT2A | |
| Isoxaflutole SCHEMBL19859097 | 0.84 | DHODH (0.44) | DHODHCACNA1BNR1I2MEN1KMT2A | |
| Isoxaflutole SCHEMBL4661049 | 0.83 | DHODH (0.43) | DHODHCACNA1BNR1I2MEN1KMT2A | |
| Isoxaflutole SCHEMBL15798456 | 0.82 | DHODH (0.43) | DHODHCACNA1BNR1I2MEN1KMT2A | |
| SCHEMBL8605423 | 0.79 | DHODH (0.45) | DHODHCACNA1BNR1I2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487303-A1 | METHOD OF CONTROLLING PLANTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-29 | — | — | EP | disclosed |
| EP-3280260-A1 | HERBICIDAL MIXTURES | Syngenta Participations AG (CH) | 2018-02-14 | — | — | EP | disclosed |
| EP-3277089-A1 | HERBICIDAL MIXTURES | Syngenta Participations AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| WO-2018015476-A1 | METHOD OF CONTROLLING PLANTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-25 | — | — | WO | disclosed |
| WO-2016162265-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-13 | — | — | WO | disclosed |
| WO-2016156241-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |