SCHEMBL1811581

SCHEMBL1811581

CCOCc1cc(OC)ccc1C=CC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.49
PTGER3 P43115 1/20 0.49
PTGER2 P43116 1/20 0.49
THRB P10828 1/20 0.48
ATM Q13315 1/20 0.48
MAPT P10636 5/20 0.47
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LY96 Q9Y6Y9 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
JUN P05412 1/20 0.43
NFKB1 P19838 1/20 0.43
BACE1 P56817 2/20 0.43
MAPK1 P28482 1/20 0.43
TNFRSF1A P19438 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1811578 1.00 PTGER4 (0.49) PTGER4PTGER3PTGER2THRBATM
SCHEMBL285246 0.87 PTGER4 (0.54) PTGER4PTGER3PTGER2THRBATM
SCHEMBL285247 0.87 PTGER4 (0.54) PTGER4PTGER3PTGER2THRBATM
SCHEMBL158083 0.87 PTGER4 (0.47) PTGER4PTGER3PTGER2THRBATM
SCHEMBL489473 0.83 PTGER4 (0.51) PTGER4PTGER3PTGER2THRBATM
SCHEMBL489472 0.83 PTGER4 (0.51) PTGER4PTGER3PTGER2THRBATM
SCHEMBL26046301 0.83 PTGER4 (0.53) PTGER4PTGER3PTGER2THRBATM
SCHEMBL9556879 0.83 PTGER4 (0.44) PTGER4PTGER3PTGER2THRBATM
SCHEMBL6367849 0.81 PTGER4 (0.49) PTGER4PTGER3PTGER2THRBATM
SCHEMBL5178122 0.81 PTGER4 (0.49) PTGER4PTGER3PTGER2THRBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2324863-B1 Method for producing artificial skin SHISEIDO CO LTD (JP) 2013-07-31 EP disclosed
EP-2324863-A1 Method for producing artificial skin SHISEIDO COMPANY, LTD. (JP) 2011-05-25 EP disclosed
US-7645595-B2 Method of production of artificial skin SHISEIDO COMPANY, LTD. (JP) 2010-01-12 US disclosed
US-20080248571-A1 Method of Production of Artificial Skin SHISEIDO COMPANY, LTD. (JP) 2008-10-09 US disclosed
US-20060159782-A1 Material for promoting skin basement formation SHISEIDO COMPANY, LTD. (JP) 2006-07-20 US disclosed
US-20040038859-A1 Agent promoting the formation of skin basement membrane, agents promoting the formation of artificial skin and process for producing artificial skin SHISEIDO CO., LTD. (JP) 2004-02-26 US disclosed
US-20020193875-A1 Agent promoting the formation of skin basement membrane, agents promoting the formation of artificial skin and process for producing artificial skin SHISEIDO COMPANY, LTD. (JP) 2002-12-19 US disclosed
EP-1180371-A1 AGENTS PROMOTING THE FORMATION OF SKIN BASEMENT MEMBRANE, AGENTS PROMOTING THE FORMATION OF ARTIFICIAL SKIN AND PROCESS FOR PRODUCING ARTIFICIAL SKIN SHISEIDO COMPANY LIMITED (JP) 2002-02-20 EP disclosed
EP-0804145-A4 OAT OIL COMPOSITIONS WITH USEFUL DERMATOLOGICAL PROPERTIES NURTURE INC (US) 1999-05-26 EP disclosed
EP-0804145-A1 OAT OIL COMPOSITIONS WITH USEFUL DERMATOLOGICAL PROPERTIES NURTURE, Inc. (US) 1997-11-05 EP disclosed
US-5620692-A MIXING WATER, CRUDE OAT OIL AND A PROTENEOUS EMULSIFIER, FORMING MIXTURE, AGITATING, SOLVENT EXTRACTION OF OAT OIL, EVAPORATING THE SOLVENT, WASHING AND DEODERIZING; ULTRAVIOLET RADIATION BLOCKER; ANTIAGING, ANTICANCER AGENT NURTURE, INC. (US) 1997-04-15 US disclosed
WO-1995017162-A1 OAT OIL COMPOSITIONS WITH USEFUL DERMATOLOGICAL PROPERTIES NURTURE, INC. (US) 1995-06-29 WO disclosed
WO-1994021222-A1 SUNBLOCKING, EMULSIFYING PROTEINACEOUS PARTICULATE LOTION AND MANUFACTURE NURTURE, INC. (US) 1994-09-29 WO disclosed