Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.68 |
| ▸ | PIK3CA | P42336 | 18/20 | 0.68 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.66 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.66 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.66 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.66 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.66 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.66 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.66 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.51 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.51 |
| ▸ | RICTOR | Q6R327 | 3/20 | 0.48 |
| ▸ | MAPKAP1 | Q9BPZ7 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117967 | 1.00 | MTOR (0.68) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL1311369 | 0.92 | MTOR (0.80) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL1311809 | 0.92 | MTOR (0.80) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL18117888 | 0.85 | PIK3CA (0.91) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL18117970 | 0.83 | PIK3CA (0.65) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL18117971 | 0.83 | PIK3CA (0.65) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL18117916 | 0.83 | MTOR (0.85) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL18117897 | 0.83 | MTOR (0.85) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL20692989 | 0.81 | PIK3CA (1.00) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL29879892 | 0.81 | PIK3CA (1.00) | MTORPIK3CAPIK3CBPIK3CDPIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364302-B1 | TRIAZINE ANALOGS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIV BASEL (CH) | 2016-10-05 | — | — | EP | disclosed |