SCHEMBL18119486

SCHEMBL18119486

c1ccc(-n2c(-c3ccc4c5ccccc5n(-c5ccccc5)c4c3)nnc2-c2ccc3c4ccccc4n(-c4ccccc4)c3c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.58
ATM Q13315 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
AVPR1A P37288 1/20 0.50
HPGD P15428 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
ALDH1A1 P00352 4/20 0.45
HSD17B10 Q99714 3/20 0.45
TSHR P16473 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
GLA P06280 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
OXTR P30559 1/20 0.39
OPRD1 P41143 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18538735 0.95 KDM4E (0.53) KDM4EATML3MBTL1AVPR1AHPGD
SCHEMBL17636651 0.94 KDM4E (0.51) KDM4EATML3MBTL1AVPR1AHPGD
SCHEMBL10100853 0.92 KDM4E (0.64) KDM4EATML3MBTL1AVPR1AHPGD
SCHEMBL18538731 0.92 AVPR1A (0.50) KDM4EATML3MBTL1AVPR1AHPGD
SCHEMBL18119488 0.92 AVPR1A (0.50) KDM4EATML3MBTL1AVPR1AHPGD
SCHEMBL29622127 0.90 KDM4E (0.62) KDM4EATML3MBTL1AVPR1AHPGD
SCHEMBL888033 0.90 KDM4E (0.62) KDM4EATML3MBTL1AVPR1AHPGD
SCHEMBL18119487 0.89 MDM2 (0.46) KDM4EATML3MBTL1AVPR1AHPGD
SCHEMBL18119493 0.89 AVPR1A (0.48) KDM4EATML3MBTL1AVPR1AHPGD
SCHEMBL10111066 0.89 KDM4E (0.56) KDM4EATML3MBTL1AVPR1AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200168809-A1 ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-05-28 US disclosed
US-10361372-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-23 US disclosed
US-10230054-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-12 US disclosed
US-10032994-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-24 US disclosed
US-10032994-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-24 US disclosed
US-20170117483-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US disclosed
US-20170117483-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20160293845-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed
US-20160293845-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed