Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.79 |
| ▸ | EGFR | P00533 | 8/20 | 0.79 |
| ▸ | LCK | P06239 | 8/20 | 0.79 |
| ▸ | ITK | Q08881 | 6/20 | 0.79 |
| ▸ | JAK3 | P52333 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18123636 | 1.00 | BTK (0.79) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL18123620 | 0.90 | BTK (0.80) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL18123604 | 0.90 | BTK (0.80) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL441767 | 0.88 | BTK (1.00) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL29663572 | 0.88 | BTK (1.00) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL409251 | 0.88 | BTK (1.00) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL409249 | 0.88 | BTK (1.00) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL459846 | 0.88 | BTK (1.00) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL459847 | 0.88 | BTK (1.00) | BTKEGFRLCKITKJAK3 | |
| SCHEMBL410335 | 0.88 | BTK (1.00) | BTKEGFRLCKITKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016154998-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE, MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 安润医药科技（苏州）有限公司 | 2016-10-06 | — | — | WO | disclosed |