Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.83 |
| ▸ | PIK3CA | P42336 | 19/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282247 | 0.93 | MTOR (0.83) | MTORPIK3CA | |
| SCHEMBL2281796 | 0.91 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2284941 | 0.91 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2280656 | 0.91 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2281481 | 0.91 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2284141 | 0.90 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2284551 | 0.90 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2282185 | 0.89 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2286959 | 0.89 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2281895 | 0.89 | MTOR (1.00) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356120-B1 | IMIDAZO[1,5]NAPHTHYRIDINE COMPOUNDS, THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER (US) | 2016-10-12 | — | — | EP | claimed |