⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18124471 | 1.00 | — | — | |
| SCHEMBL18124469 | 0.77 | — | — | |
| SCHEMBL18124519 | 0.77 | — | — | |
| SCHEMBL18124521 | 0.77 | — | — | |
| SCHEMBL15423482 | 0.74 | — | — | |
| SCHEMBL24498624 | 0.73 | — | — | |
| SCHEMBL20982166 | 0.71 | — | — | |
| SCHEMBL17852569 | 0.71 | — | — | |
| SCHEMBL18323071 | 0.71 | — | — | |
| SCHEMBL17852568 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630978-B2 | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use | GILEAD SCIENCES, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20160289246-A1 | POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. | 2016-10-06 | — | — | US | disclosed |