Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812465 | 1.00 | CCR3 (0.51) | CCR3KMT2APKMALDH1A1L3MBTL1 | |
| SCHEMBL1805808 | 0.89 | CCR3 (0.56) | CCR3KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL1805810 | 0.89 | CCR3 (0.56) | CCR3KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL1807556 | 0.86 | CCR3 (0.59) | CCR3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL1807554 | 0.86 | CCR3 (0.59) | CCR3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL1809490 | 0.85 | CCR3 (0.60) | CCR3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL1808939 | 0.85 | CCR3 (0.56) | CCR3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL1808933 | 0.85 | CCR3 (0.56) | CCR3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL1809496 | 0.85 | CCR3 (0.60) | CCR3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL1810211 | 0.84 | CCR3 (0.72) | CCR3KMT2AALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1801108-B9 | MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-11-20 | — | — | EP | disclosed |
| EP-1801108-B1 | MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-7935700-B2 | Morpholine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-05-03 | — | — | US | disclosed |