Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 2/20 | 0.54 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14563122 | 0.90 | TDP1 (0.64) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL17244679 | 0.89 | TDP1 (0.63) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL4922038 | 0.89 | TDP1 (0.65) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL18957208 | 0.89 | TDP1 (0.65) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL21803681 | 0.89 | TDP1 (0.65) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL23982462 | 0.89 | TDP1 (0.65) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL713333 | 0.89 | TDP1 (0.65) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL17522655 | 0.89 | TDP1 (0.65) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL22768971 | 0.88 | TDP1 (0.64) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL14253748 | 0.88 | TDP1 (0.66) | TDP1FOLH1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670755-B1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2016-10-12 | — | — | EP | disclosed |