Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134965 | 0.96 | TRIM24 (0.35) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL3674258 | 0.89 | KCNH2 (0.34) | TRIM24TRIM33ALDH1A1 | |
| Ethylene SCHEMBL17611952 | 0.85 | KCNH2 (0.33) | TRIM24TRIM33 | |
| SCHEMBL28272321 | 0.84 | TRIM24 (0.33) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL30447934 | 0.84 | MEN1 (0.34) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL4693969 | 0.83 | TRIM24 (0.32) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL10053527 | 0.78 | — | — | |
| SCHEMBL14966409 | 0.77 | TRIM24 (0.31) | TRIM24TRIM33 | |
| SCHEMBL28272317 | 0.74 | TRIM24 (0.32) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL14506033 | 0.73 | TRIM24 (0.41) | TRIM24TRIM33ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496556-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011053948-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2011-05-05 | — | — | WO | disclosed |