Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 18/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131245 | 0.93 | FGFR1 (0.39) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL18131180 | 0.92 | FGFR1 (0.41) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL18131182 | 0.92 | FGFR1 (0.41) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL18131193 | 0.85 | — | — | |
| SCHEMBL18131318 | 0.78 | FGFR3 (0.31) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16665234 | 0.77 | FGFR1 (0.54) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16654102 | 0.77 | FGFR4 (0.32) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL18138286 | 0.77 | FGFR3 (0.34) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16659612 | 0.77 | FGFR1 (0.48) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL18138288 | 0.76 | FGFR3 (0.36) | FGFR1FGFR4FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016164754-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-10-13 | — | — | WO | disclosed |