Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 9/20 | 0.46 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138855 | 0.94 | HCRTR2 (0.46) | HCRTR2NR3C1MTNR1AMTNR1BHCRTR1 | |
| SCHEMBL18138845 | 0.91 | PFKFB3 (0.51) | HCRTR2NR3C1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL20578376 | 0.90 | HCRTR2 (0.46) | HCRTR2HCRTR1ALDH1A1MAPT | |
| SCHEMBL18138801 | 0.88 | HCRTR2 (0.45) | HCRTR2NR3C1MTNR1AMTNR1BHCRTR1 | |
| SCHEMBL18138738 | 0.87 | HCRTR2 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL20323622 | 0.85 | HCRTR2 (0.58) | HCRTR2HCRTR1 | |
| SCHEMBL18138776 | 0.85 | HCRTR2 (0.47) | HCRTR2HCRTR1ALDH1A1MAPT | |
| SCHEMBL18300923 | 0.85 | PLAU (0.43) | HCRTR2NR3C1MTNR1AMTNR1BPFKFB3 | |
| SCHEMBL18138804 | 0.84 | HCRTR2 (0.53) | HCRTR2DNMT3BHCRTR1ALDH1A1 | |
| SCHEMBL18138794 | 0.83 | HCRTR2 (0.45) | HCRTR2NR3C1MTNR1AMTNR1BHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081553-A1 | SULFONAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2016-10-19 | — | — | EP | disclosed |