Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL18138985

C=C(C)C(=O)OCC(O)CS(=O)(=O)O.N

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
THRB P10828 1/20 0.37
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22138 0.98 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL10716986 0.97 TSHR (0.52) TSHRTHRBALDH1A1
SCHEMBL5689041 0.88 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL28255179 0.82 TSHR (0.31) TSHR
SCHEMBL1898257 0.81 TSHR (0.50) TSHRTHRBALDH1A1
Potassium Ion SCHEMBL18140319 0.81 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL18140803 0.81 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL18140139 0.81 TSHR (0.50) TSHRTHRBALDH1A1
Lithium Ion SCHEMBL18139799 0.81 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL18141356 0.81 TSHR (0.50) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180163056-A1 HYDROPHILIC CURABLE COMPOSITIONS MITSUI CHEMICALS, INC. (JP) 2018-06-14 US disclosed
US-20180036995-A1 HYDROPHILIC MONOLAYER FILM WITH OPTICAL FUNCTIONALITY AND STACK OF THE SAME MITSUI CHEMICALS, INC. (JP) 2018-02-08 US disclosed
EP-3270192-A1 HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF Mitsui Chemicals, Inc. (JP) 2018-01-17 EP disclosed
EP-3081578-A1 COMPOSITION FOR HYDROPHILIC CURED PRODUCT Mitsui Chemicals, Inc. (JP) 2016-10-19 EP disclosed