SCHEMBL181403

SCHEMBL181403

Nc1ncccc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 1.00
KDM4E B2RXH2 3/20 0.63
TDP1 Q9NUW8 1/20 0.63
ALDH1A1 P00352 5/20 0.61
ALOX15 P16050 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
CYP3A4 P08684 1/20 0.61
MAPT P10636 1/20 0.61
TSHR P16473 1/20 0.61
BLM P54132 1/20 0.61
AGER Q15109 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
PRKCI P41743 2/20 0.61
LMNA P02545 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
DHODH Q02127 2/20 0.50
MYC P01106 1/20 0.49
ALOX12 P18054 1/20 0.46
CYP2C9 P11712 1/20 0.46
KDM6B O15054 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29530139 1.00 NAPRT (1.00) NAPRTKDM4ETDP1ALDH1A1ALOX15
SCHEMBL30792465 1.00 NAPRT (1.00) NAPRTKDM4ETDP1ALDH1A1ALOX15
SCHEMBL219457 1.00 NAPRT (1.00) NAPRTKDM4ETDP1ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL28305203 0.98 NAPRT (0.96) NAPRTKDM4ETDP1ALDH1A1ALOX15
SCHEMBL27926024 0.98 NAPRT (0.96) NAPRTKDM4ETDP1ALDH1A1ALOX15
SCHEMBL27881680 0.98 NAPRT (0.96) NAPRTKDM4ETDP1ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL29398658 0.98 NAPRT (0.96) NAPRTKDM4ETDP1ALDH1A1ALOX15
Carbamic Acid SCHEMBL27881895 0.98 NAPRT (0.96) NAPRTKDM4ETDP1ALDH1A1ALOX15
Nitrous Acid SCHEMBL27649581 0.92 NAPRT (0.85) NAPRTKDM4ETDP1ALDH1A1ALOX15
Quinolinic Acid SCHEMBL28273991 0.91 NAPRT (0.82) NAPRTKDM4ETDP1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2840 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
US-20250345299-A1 COMBINATION AND COMPOSITION COMPRISING NICOTINIC ACID OR DERIVATIVE THEREOF AND FATTY ACID OR DERIVATIVE THEREOF T OMEGA AS (NO) 2025-11-13 US claimed
US-20250229219-A1 CARBON DIOXIDE CAPTURE AGENT CONTAINING TWO TYPES OF AMINE COMPOUNDS AND CARBON DIOXIDE CAPTURE METHOD USING THE SAME KOREA INSTITUTE OF ENERGY RESEARCH (KR) 2025-07-17 US claimed
CN-120058211-A Treatment process of heavy metal polluted sludge 江苏丰衡科技有限公司 2025-05-30 CN claimed
CN-119822991-A Fatty acid salt structure-containing compound, solid composition and application thereof 江苏万邦医药科技有限公司 2025-04-15 CN claimed
CN-119522096-A Combinations and compositions comprising niacin or derivatives thereof and fatty acids or derivatives thereof T欧米伽股份有限公司 2025-02-25 CN claimed
CN-119019453-B Iron ion stabilizer for oilfield fracturing and preparation method and application thereof 东营众悦石油科技有限公司 2025-01-07 CN claimed
CN-119081560-A High-weather-resistance flexible fabric membrane material and preparation method thereof 中成空间(深圳)智能技术有限公司 2024-12-06 CN claimed
CN-119019453-A Iron ion stabilizer for oilfield fracturing and preparation method and application thereof 东营众悦石油科技有限公司 2024-11-26 CN claimed
CN-118406036-A Temperature-resistant salt-resistant thick oil viscosity reducer and preparation method and application thereof 东营市盛聚化工有限责任公司 2024-07-30 CN claimed
US-6362393-B1 Methods for generating doubled haploid plants NORTHWEST PLANT BREEDING COMPANY 2002-03-26 US claimed
US-20010041685-A1 Mucin synthesis inhibitors GENAERA CORPORATION 2001-11-15 US claimed
WO-2001054685-A1 MUCIN SYNTHESIS INHIBITORS GENAERA CORPORATION (US) 2001-08-02 WO claimed
EP-1112347-A1 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS Northwest Plant Breeding Co. (US) 2001-07-04 EP claimed
WO-2001014518-A2 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING CO. (US) 2001-03-01 WO claimed
WO-2000014202-A1 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING COMPANY (US) 2000-03-16 WO claimed
US-5708137-A Reagent and method for determining activity of herpes protease G.D. SEARLE & CO. (US) 1998-01-13 US claimed
US-5506115-A FLUOROGENIC PEPTIDES AS SUBSTRATES FOR ASSAY G. D. SEARLE & CO. (US) 1996-04-09 US claimed
EP-0113242-B1 CEPHALOSPORIN DERIVATIVES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-11-08 EP claimed
EP-0113242-A2 Cephalosporin derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-07-11 EP claimed