SCHEMBL181506

SCHEMBL181506

CCCCCCCCCCCCCCCCC(C(=O)O)C1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.50
PPARD Q03181 1/20 0.50
ZDHHC20 Q5W0Z9 1/20 0.50
ZDHHC2 Q9UIJ5 1/20 0.50
GPR84 Q9NQS5 3/20 0.47
FFAR1 O14842 1/20 0.47
MAPT P10636 1/20 0.46
EPHX1 P07099 8/20 0.44
EPHX2 P34913 2/20 0.44
TSHR P16473 1/20 0.43
ACE2 Q9BYF1 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.43
NAAA Q02083 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861922 1.00 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL28418904 1.00 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL5385696 1.00 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL8736617 1.00 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL2555276 1.00 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL10494941 1.00 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL2555573 1.00 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL3272020 1.00 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL8735257 0.98 LCK (0.52) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL5375201 0.98 LCK (0.52) LCKPPARDZDHHC20ZDHHC2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3601497-B1 COMPOSITION, METHOD AND USE INNOSPEC LTD (GB) 2024-05-15 EP disclosed
EP-3601490-B1 METHOD AND USE TO PREVENT DEPOSITS IN ENGINE INNOSPEC LTD (GB) 2023-09-27 EP disclosed
EP-3601212-B1 COMPOSITION, METHOD AND USE INNOSPEC LTD (GB) 2023-09-06 EP disclosed
US-11186791-B2 Composition, method and use INNOSPEC LIMITED (GB) 2021-11-30 US disclosed
US-11174442-B2 Fuel compositions, methods and uses relating to quaternary ammonium salt additives for fuel used in spark ignition engines INNOSPEC LIMITED (GB) 2021-11-16 US disclosed
US-11015137-B2 Composition, method and use INNOSPEC LIMITED (GB) 2021-05-25 US disclosed
US-20200377810-A1 METHOD AND USE TO PREVENT DEPOSITS IN ENGINE INNOSPEC LIMITED (GB) 2020-12-03 US disclosed
US-20200354642-A1 Fuel Composition Comprising Detergent and Quaternary Ammonium Salt Additive INNOSPEC LIMITED (GB) 2020-11-12 US disclosed
US-20200157445-A1 COMPOSITION, METHOD AND USE INNOSPEC LIMITED (GB) 2020-05-21 US disclosed
US-20200040270-A1 COMPOSITION, METHOD AND USE INNOSPEC LIMITED (GB) 2020-02-06 US disclosed
US-4663063-A OIL AND FUEL ADDITIVES THE LUBRIZOL CORPORATION (US) 1987-05-05 US disclosed
US-4659338-A ASHLESS DISPERSANT AND ALKALI OR ALKALINE EARTH METAL COMPOUND THE LUBRIZOL CORPORATION (US) 1987-04-21 US disclosed
WO-1987001126-A1 FUEL PRODUCTS THE LUBRIZOL CORPORATION (US) 1987-02-26 WO disclosed
EP-0203969-A1 ALKYL PHENOL AND AMINO COMPOUND COMPOSITIONS AND TWO-CYCLE ENGINE OILS AND FUELS CONTAINING SAME. LUBRIZOL CORP (US) 1986-12-10 EP disclosed
WO-1986003220-A1 ALKYL PHENOL AND AMINO COMPOUND COMPOSITIONS AND TWO-CYCLE ENGINE OILS AND FUELS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1986-06-05 WO disclosed
EP-0148844-A1 ALKYL PHENOL AND AMINO PHENOL COMPOSITIONS AND TWO-CYCLE ENGINE OILS AND FUELS CONTAINING SAME. LUBRIZOL CORP (US) 1985-07-24 EP disclosed
WO-1984003901-A1 ALKYL PHENOL AND AMINO PHENOL COMPOSITIONS AND TWO-CYCLE ENGINE OILS AND FUELS CONTAINING SAME LUBRIZOL CORP (US) 1984-10-11 WO disclosed
EP-0062820-A2 Polyamide film and process for the manufacture thereof BAYER AG (DE) 1982-10-20 EP disclosed
US-4200545-A Amino phenol-detergent/dispersant combinations and fuels and lubricants containing same THE LUBRIZOL CORPORATION (US) 1980-04-29 US disclosed
US-4100082-A Lubricants containing amino phenol-detergent/dispersant combinations THE LUBRIZOL CORPORATION (US) 1978-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200040270-A1 COMPOSITION, METHOD AND USE NR1H3, NR1H2, NR1I2 LCK 1083/4885PPARD 1981/4885ZDHHC20 509/4885
US-11015137-B2 Composition, method and use NR1H3, NR1H2, NR1I2 LCK 1083/4885PPARD 1981/4885ZDHHC20 509/4885
US-11186791-B2 Composition, method and use C5, H1-0, C9 LCK 2505/4885PPARD 3780/4885ZDHHC20 2039/4885
US-20200157445-A1 COMPOSITION, METHOD AND USE C5, H1-0, C9 LCK 2505/4885PPARD 3780/4885ZDHHC20 2039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.