SCHEMBL18151865

SCHEMBL18151865

NC(=O)CCCCCCCCCS

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.57
SOAT1 P35610 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
FAAH O00519 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
HDAC3 O15379 7/20 0.42
HDAC1 Q13547 7/20 0.42
HDAC2 Q92769 7/20 0.42
HDAC10 Q969S8 7/20 0.42
HDAC11 Q96DB2 7/20 0.42
HDAC8 Q9BY41 7/20 0.42
HDAC6 Q9UBN7 7/20 0.42
HDAC4 P56524 6/20 0.41
HDAC7 Q8WUI4 6/20 0.41
HDAC9 Q9UKV0 6/20 0.41
HDAC5 Q9UQL6 6/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30293939 1.00 FOLH1 (0.57) FOLH1SOAT1MEN1KMT2AFAAH
SCHEMBL11592376 1.00 FOLH1 (0.57) FOLH1SOAT1MEN1KMT2AFAAH
SCHEMBL11165736 1.00
SCHEMBL1929821 1.00 FOLH1 (0.57) FOLH1SOAT1MEN1KMT2AFAAH
SCHEMBL18151528 1.00 FOLH1 (0.57) FOLH1SOAT1MEN1KMT2AFAAH
SCHEMBL10384055 1.00 FOLH1 (0.57) FOLH1SOAT1MEN1KMT2AFAAH
SCHEMBL18151525 1.00 FOLH1 (0.57) FOLH1SOAT1MEN1KMT2AFAAH
SCHEMBL4224660 1.00 FOLH1 (0.57) FOLH1SOAT1MEN1KMT2AFAAH
SCHEMBL1679976 0.97
SCHEMBL30466827 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10465030-B2 Nanoparticles complexed with functionalizable enhanced affinity ligands and use thereof NEXDOT (FR) 2019-11-05 US disclosed
US-20160304648-A1 NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF NEXDOT (FR) 2016-10-20 US disclosed