Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877956 | 0.81 | SLC2A1 (0.65) | SLC2A1GAAPOLBTP53MAPK10 | |
| SCHEMBL31484197 | 0.80 | SLC2A1 (0.47) | SLC2A1GAATP53MAPK10KMT2A | |
| SCHEMBL9878839 | 0.80 | CYP1A2 (0.66) | SLC2A1GAAPOLBTP53MAPK10 | |
| Hydrochloric Acid SCHEMBL9878054 | 0.80 | SLC2A1 (0.64) | SLC2A1GAAPOLBTP53MAPK10 | |
| SCHEMBL5309423 | 0.79 | TTR (0.52) | GAAPOLBKMT2AMEN1MAPT | |
| SCHEMBL5483254 | 0.78 | ABCG2 (0.69) | SLC2A1KMT2AMEN1 | |
| SCHEMBL5309420 | 0.77 | KDM4E (0.54) | GAAPOLBKMT2AMEN1ATM | |
| SCHEMBL15489512 | 0.77 | MAPK10 (0.57) | SLC2A1MAPK10HTTLRRK2MAPK11 | |
| SCHEMBL4595367 | 0.75 | KDR (0.47) | TP53MAPK10KMT2AMEN1LMNA | |
| SCHEMBL10939229 | 0.75 | TSHR (0.67) | SLC2A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |