SCHEMBL1815390

SCHEMBL1815390

CCCCCc1ccc(Br)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.59
ADRA2A P08913 2/20 0.59
ADORA3 P0DMS8 2/20 0.59
TACR2 P21452 2/20 0.59
SLC6A2 P23975 2/20 0.59
SLC6A4 P31645 2/20 0.59
SLC6A3 Q01959 2/20 0.59
ALDH1A1 P00352 2/20 0.59
LMNA P02545 2/20 0.59
HTR2A P28223 2/20 0.59
KDM4E B2RXH2 1/20 0.59
SHBG P04278 1/20 0.59
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
HSPD1 P10809 1/20 0.59
ADRB3 P13945 1/20 0.59
HTR2C P28335 1/20 0.59
HSPE1 P61604 1/20 0.59
HIF1A Q16665 1/20 0.59
TST Q16762 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15200865 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL2831631 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL7471227 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL340275 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL4191545 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL349345 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL11523006 0.98 ESR1 (0.57) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL15353198 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL7781659 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL3178688 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920813-B Photo-thermal response chiral photosensitive liquid crystal dopant containing azobenzene binaphthyl 湘潭大学 2023-08-22 CN claimed
CN-112920813-A Photo-thermal responsive chiral photosensitive liquid crystal dopant containing azobenzene binaphthalene 湘潭大学 2021-06-08 CN claimed
CN-111362833-A Dianthracene D-delta-A type deep blue organic fluorescent material and preparation method and application thereof 陕西师范大学 2020-07-03 CN claimed
CN-105185911-B A kind of polymer solar battery based on solvent doping and preparation method thereof 电子科技大学 2017-11-17 CN claimed
CN-105185911-A Polymer solar battery based on solvent doping, and preparation method thereof UNIV ELECTRONIC SCIENCE & TECH 2015-12-23 CN claimed
CN-102432451-B Pyrene type asymmetrical disc-like luminous compound and preparation method thereof UNIV BEIJING SCIENCE & TECH 2013-10-16 CN claimed
CN-102432451-A Pyrene type asymmetrical disc-like luminous compound and preparation method thereof UNIV BEIJING SCIENCE & TECH 2012-05-02 CN claimed
WO-2026086794-A1 ANTIMICROBIAL COMPOUNDS AND METHODS OF USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2026-04-30 WO disclosed
CN-113677657-B Polymerizable liquid crystal composition, liquid crystal display element, and compound 石家庄诚志永华显示材料有限公司 2025-04-01 CN disclosed
CN-117736247-A Preparation method of aryl substituted ferrocene monophosphine ligand containing planar chirality 南京大学 2024-03-22 CN disclosed
US-11667840-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
CN-111362833-B Double anthracene D-delta-A type deep blue organic fluorescent material and preparation method and application thereof 陕西师范大学 2023-04-25 CN disclosed
US-11186773-B2 Liquid crystal compositions, mixtures, elements, and dimmable devices NITTO DENKO CORPORATION (JP) 2021-11-30 US disclosed
EP-0215120-A1 CYCLOHEXANE DERIVATIVES. MERCK PATENT GMBH (DE) 1987-03-25 EP disclosed
WO-1986005486-A1 CYCLOHEXANE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-09-25 WO disclosed
US-4154697-A Liquid crystalline hexahydroterphenyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1979-05-15 US disclosed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US disclosed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US disclosed
US-3992536-A SEDATIVES AND MUSCLE RELAXANTS BOEHRINGER INGELHEIM GMBH (DT) 1976-11-16 US disclosed
US-3931185-A SEDATIVES, MUSCLE RELAXANT BOEHRINGER INGELHEIM GMBH (DT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667840-B2 Liquid-crystalline medium FES, BLM, CXCL12 ESR1 3951/4885ADRA2A 4094/4885ADORA3 4153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.