Bicarbonate

Bicarbonate

SCHEMBL1815439

O=C([O-])[O-].O=C([O-])[O-].[Ca+2].[Li+].[Na+]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA4 P22748 5/20 0.55
FAHD1 Q6P587 1/20 0.55
CA1 P00915 2/20 0.50
MEN1 O00255 1/20 0.43
LDHA P00338 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
LMNA P02545 2/20 0.40
CASP1 P29466 1/20 0.40
FFAR3 O14843 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL262023 0.94
Bicarbonate SCHEMBL5072497 0.94 CA4 (0.60) CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL2132949 0.94 CA4 (0.60) CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL9059393 0.89 CA4 (0.70) CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL8503801 0.89
Bicarbonate SCHEMBL30589 0.89
Bicarbonate SCHEMBL14578981 0.89 CA4 (0.55) CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL1817944 0.89 CA4 (0.55) CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL18989584 0.89 CA4 (0.55) CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL14562695 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102460803-B Fuel cell systems and processes of operating fuel cell systems SHELL OIL CO 2014-12-10 CN disclosed
US-20140242482-A1 SYSTEMS AND PROCESSES FOR OPERATING FUEL CELL SYSTEMS SHELL OIL COMPANY (US) 2014-08-28 US disclosed
US-8795912-B2 Systems and processes for operating fuel cell systems SHELL OIL COMPANY (US) 2014-08-05 US disclosed
US-8632922-B2 Systems and processes for operating fuel cell systems SHELL OIL COMPANY (US) 2014-01-21 US disclosed
US-8563186-B2 Systems and processes of operating fuel cell systems SHELL OIL COMPANY (US) 2013-10-22 US disclosed
US-20130177824-A1 SYSTEMS AND PROCESSES OF OPERATING FUEL CELL SYSTEMS SHELL OIL COMPANY (US) 2013-07-11 US disclosed
CN-102804471-A Systems And Processes Of Operating Fuel Cell Systems SHELL INT RESEARCH 2012-11-28 CN disclosed
CN-102460803-A Systems and processes of operating fuel cell systems SHELL OIL CO 2012-05-16 CN disclosed
CN-102460808-A Systems and processes for operating fuel cell systems SHELL OIL CO 2012-05-16 CN disclosed
EP-2443690-A1 SYSTEMS AND PROCESSES OF OPERATING FUEL CELL SYSTEMS Shell Oil Company (US) 2012-04-25 EP disclosed
EP-2443689-A1 SYSTEMS AND PROCESSES FOR OPERATING FUEL CELL SYSTEMS Shell Oil Company (US) 2012-04-25 EP disclosed
US-20110111315-A1 SYSTEMS AND PROCESSES OF OPERATING FUEL CELL SYSTEMS SHELL OIL COMPANY 2011-05-12 US disclosed
US-20110111314-A1 SYSTEMS AND PROCESSES FOR OPERATING FUEL CELL SYSTEMS SHELL OIL COMPANY 2011-05-12 US disclosed
US-20110104577-A1 SYSTEMS AND PROCESSES FOR OPERATING FUEL CELL SYSTEMS SHELL OIL COMPANY 2011-05-05 US disclosed
WO-2010147886-A1 SYSTEMS AND PROCESSES FOR OPERATING FUEL CELL SYSTEMS SHELL OIL COMPANY (US) 2010-12-23 WO disclosed
WO-2010147885-A1 SYSTEMS AND PROCESSES OF OPERATING FUEL CELL SYSTEMS SHELL OIL COMPANY (US) 2010-12-23 WO disclosed