SCHEMBL18154558

SCHEMBL18154558

CC(C)(C)OC(=O)N1CCc2cc3cc(-n4ccc(OCc5ccc(F)cn5)cc4=O)ccc3n2CC1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18154530 0.91 MCHR1 (0.49) MCHR1
SCHEMBL18154576 0.85 MCHR1 (0.58) MCHR1
SCHEMBL31573841 0.85 MCHR1 (0.58) MCHR1
SCHEMBL18154586 0.85 MCHR1 (0.46) MCHR1
SCHEMBL18154524 0.85 MCHR1 (0.50) MCHR1
SCHEMBL9968762 0.84 MCHR1 (0.51) MCHR1
SCHEMBL21981720 0.83 MCHR1 (0.47) MCHR1
SCHEMBL21981716 0.83 MCHR1 (0.47) MCHR1
SCHEMBL18154568 0.83 MCHR1 (0.66) MCHR1
Maleic Acid SCHEMBL31573863 0.83 MCHR1 (0.53) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3286193-B1 INDOLE DERIVATIVES RICHTER GEDEON NYRT (HU) 2020-05-27 EP disclosed
EP-3286193-A1 INDOLE DERIVATIVES Richter Gedeon Nyrt. (HU) 2018-02-28 EP disclosed
WO-2016166684-A1 INDOLE DERIVATIVES RICHTER GEDEON NYRT. (HU) 2016-10-20 WO disclosed