Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154568 | 0.90 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL18154534 | 0.89 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL30701156 | 0.89 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL21981715 | 0.88 | MCHR1 (0.56) | MCHR1 | |
| SCHEMBL30701057 | 0.88 | MCHR1 (0.54) | MCHR1 | |
| SCHEMBL18154521 | 0.88 | MCHR1 (0.54) | MCHR1 | |
| SCHEMBL21064792 | 0.86 | MCHR1 (0.54) | MCHR1 | |
| SCHEMBL18154563 | 0.85 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL18154582 | 0.85 | MCHR1 (0.58) | MCHR1 | |
| SCHEMBL30701113 | 0.85 | MCHR1 (0.58) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023242810-A1 | MCHR1 ANTAGONISTS FOR THE TREATMENT OF PRADER-WILLI SYNDROME | RICHTER GEDEON NYRT. (HU) | 2023-12-21 | — | — | WO | claimed |
| EP-3286193-B1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2020-05-27 | — | — | EP | claimed |
| EP-4540251-A1 | CRYSTALLINE FORMS OF 4-[(5-CHLOROPYRIDIN-2-YL)METHOXY]-1-[3-(PROPAN-2-YL)-1H,2H,3H,4H,5H-[1,4]DIAZEPINO[1,7-A]INDOL-9-YL]-1,2-DIHYDROPYRIDIN-2-ONE AND SALTS THEREOF, METHOD OF PREPARATION, AND USES THEREOF | Richter Gedeon Nyrt. (HU) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023242809-A1 | CRYSTALLINE FORMS OF 4-[(5-CHLOROPYRIDIN-2-YL)METHOXY]-1-[3-(PROPAN-2-YL)-1H,2H,3H,4H,5H-[1,4]DIAZEPINO[1,7-A]INDOL-9-YL]-1,2-DIHYDROPYRIDIN-2-ONE AND SALTS THEREOF, METHOD OF PREPARATION, AND USES THEREOF | RICHTER GEDEON NYRT. (HU) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023242810-A1 | MCHR1 ANTAGONISTS FOR THE TREATMENT OF PRADER-WILLI SYNDROME | RICHTER GEDEON NYRT. (HU) | 2023-12-21 | — | — | WO | disclosed |
| EP-3286193-A1 | INDOLE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016166684-A1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2016-10-20 | — | — | WO | disclosed |