Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29769046 | 0.81 | CYP1A2 (0.56) | RAB9AMAOBALDH1A1MAPT | |
| SCHEMBL351009 | 0.81 | CYP1A2 (0.56) | RAB9AMAOBALDH1A1MAPT | |
| SCHEMBL31658841 | 0.81 | MAOB (0.54) | APPNPC1RAB9AMAOBPOLB | |
| SCHEMBL26099232 | 0.81 | APP (0.51) | APPNPC1RAB9AMAOBPOLB | |
| SCHEMBL16012226 | 0.81 | MAOB (0.54) | APPNPC1RAB9AMAOBPOLB | |
| SCHEMBL30615152 | 0.80 | — | — | |
| SCHEMBL2312335 | 0.80 | — | — | |
| SCHEMBL4306905 | 0.78 | APP (0.49) | APPNPC1RAB9AMAOBPOLB | |
| SCHEMBL28366776 | 0.78 | APP (0.65) | APPNPC1RAB9AMAOBPOLB | |
| SCHEMBL26098902 | 0.77 | NPC1 (0.49) | APPNPC1RAB9AMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286193-A1 | INDOLE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016166684-A1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2016-10-20 | — | — | WO | disclosed |