⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579552 | 0.71 | MEN1 (0.36) | — | |
| SCHEMBL4395858 | 0.67 | — | — | |
| SCHEMBL2058548 | 0.67 | — | — | |
| SCHEMBL6961764 | 0.63 | — | — | |
| SCHEMBL21639792 | 0.63 | — | — | |
| SCHEMBL11003874 | 0.63 | MEN1 (0.55) | — | |
| SCHEMBL7644335 | 0.63 | — | — | |
| SCHEMBL16342020 | 0.60 | — | — | |
| SCHEMBL1292537 | 0.60 | — | — | |
| SCHEMBL9328591 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283550-B1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| EP-3294803-B1 | GUANIDINE GROUP CONTAINING CATALYST | SIKA TECH AG (CH) | 2020-12-09 | — | — | EP | disclosed |
| US-10414875-B2 | Catalyst containing guanidine groups | SIKA TECHNOLOGY AG (CH) | 2019-09-17 | — | — | US | disclosed |
| US-10392480-B2 | Catalyst containing amidine groups | SIKA TECHNOLOGY AG (CH) | 2019-08-27 | — | — | US | disclosed |
| US-20180171082-A1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2018-06-21 | — | — | US | disclosed |
| US-20180148545-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2018-05-31 | — | — | US | disclosed |
| EP-3294803-A1 | CATALYST CONTAINING GUANIDINE GROUPS | Sika Technology AG (CH) | 2018-03-21 | — | — | EP | disclosed |
| EP-3283550-A1 | AMIDINE-GROUP CONTAINING CATALYST | Sika Technology AG (CH) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016180840-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016166336-A1 | AMIDINE-GROUP CONTAINING CATALYST | SIKA TECHNOLOGY AG (CH) | 2016-10-20 | — | — | WO | disclosed |