Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14769622 | 1.00 | NPSR1 (0.51) | NPSR1NPC1RAB9ATP53POLB | |
| SCHEMBL18155184 | 0.85 | ESR1 (0.54) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL22251644 | 0.85 | ESR1 (0.54) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL14769640 | 0.85 | ESR1 (0.54) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL18591277 | 0.77 | NPSR1 (0.64) | NPSR1NPC1RAB9ATP53POLB | |
| SCHEMBL18710627 | 0.76 | ESR1 (0.52) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL259126 | 0.75 | NPSR1 (0.55) | NPSR1NPC1RAB9ATP53POLB | |
| SCHEMBL28401935 | 0.75 | NPSR1 (0.57) | NPSR1NPC1RAB9ATP53POLB | |
| SCHEMBL31122583 | 0.74 | NPSR1 (0.63) | NPSR1NPC1RAB9AHSD17B10LMNA | |
| SCHEMBL10326684 | 0.74 | NPSR1 (0.63) | NPSR1NPC1RAB9AHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469861-B2 | Cell-free preparation of carbapenems | GREENLIGHT BIOSCIENCES, INC. (US) | 2016-10-18 | — | — | US | disclosed |