Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14688216 | 0.83 | KDM4E (0.46) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL18155425 | 0.77 | KDM4E (0.41) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL2359337 | 0.75 | KDM4E (0.56) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL22529407 | 0.75 | KDM4E (0.52) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL6625704 | 0.70 | PARP1 (0.47) | PARP1MAPK10RIPK1BRD4 | |
| SCHEMBL5271427 | 0.70 | KDM4E (0.54) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL5273779 | 0.67 | KDM4E (0.50) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL12440714 | 0.65 | AR (0.47) | KDM4ELMNAHPGDGAAPARP1 | |
| SCHEMBL7244979 | 0.64 | NQO2 (0.46) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL12440434 | 0.64 | KDM4E (0.57) | KDM4ELMNAALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531029-B1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH INC (US) | 2016-10-19 | — | — | EP | disclosed |