Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 8/20 | 0.35 |
| ▸ | F13A1 | P00488 | 7/20 | 0.35 |
| ▸ | TGM1 | P22735 | 7/20 | 0.35 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360361 | 0.85 | CCNB2 (0.36) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL29896524 | 0.79 | TP53 (0.39) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL30788004 | 0.79 | TP53 (0.37) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL22529425 | 0.79 | TP53 (0.37) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL2360890 | 0.79 | TP53 (0.39) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL30787995 | 0.76 | CCNB2 (0.39) | TGM2F13A1TGM1TGM3CCNB2 | |
| SCHEMBL2360130 | 0.76 | CCNB2 (0.39) | TGM2F13A1TGM1TGM3CCNB2 | |
| SCHEMBL2359990 | 0.73 | TP53 (0.40) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL8791684 | 0.71 | TP53 (0.60) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL22529406 | 0.70 | TP53 (0.41) | CCNB2CDK1CCNB1GSK3BCCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531029-B1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH INC (US) | 2016-10-19 | — | — | EP | disclosed |