Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18156126 | 0.92 | PTGER1 (0.38) | MRGPRX4PTGER1 | |
| SCHEMBL18182434 | 0.92 | MRGPRX4 (0.37) | MRGPRX4KITRXRARXRBRXRG | |
| SCHEMBL18182631 | 0.92 | MRGPRX4 (0.36) | MRGPRX4KITRXRARXRBRXRG | |
| SCHEMBL18182609 | 0.91 | MRGPRX4 (0.42) | MRGPRX4KITKCNK3KCNK9 | |
| SCHEMBL18178782 | 0.88 | MRGPRX4 (0.36) | MRGPRX4RXRARXRBRXRGKCNK3 | |
| SCHEMBL18156348 | 0.86 | MRGPRX4 (0.42) | MRGPRX4RXRARXRBRXRGFFAR1 | |
| SCHEMBL18178603 | 0.85 | MRGPRX4 (0.37) | MRGPRX4KCNK3KCNK9PTGER1FFAR1 | |
| SCHEMBL18156495 | 0.85 | FFAR4 (0.39) | MRGPRX4RXRARXRBRXRGKCNK3 | |
| SCHEMBL18178511 | 0.85 | MRGPRX4 (0.40) | MRGPRX4RXRARXRBRXRGFFAR1 | |
| SCHEMBL18178708 | 0.85 | MRGPRX4 (0.38) | MRGPRX4KCNK3KCNK9PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081559-A1 | AROMATIC COMPOUND AND APPLICATION FOR SAME | Sumitomo Chemical Company, Limited (JP) | 2016-10-19 | — | — | EP | disclosed |