Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18182642 | 0.91 | PTGER1 (0.38) | MRGPRX4FABP3FABP4FABP5NPC1 | |
| SCHEMBL18182578 | 0.91 | MRGPRX4 (0.37) | MRGPRX4FABP3FABP4FABP5NPC1 | |
| SCHEMBL18532764 | 0.91 | MRGPRX4 (0.39) | MRGPRX4FABP3FABP4FABP5NPC1 | |
| SCHEMBL18532766 | 0.89 | MRGPRX4 (0.38) | MRGPRX4FABP3FABP4FABP5NPC1 | |
| SCHEMBL18532767 | 0.89 | MRGPRX4 (0.38) | MRGPRX4FABP3FABP4FABP5NPC1 | |
| SCHEMBL18156248 | 0.89 | SLC22A12 (0.37) | MRGPRX4FABP3FABP4FABP5NPC1 | |
| SCHEMBL18156269 | 0.88 | MRGPRX4 (0.37) | MRGPRX4FABP3FABP4FABP5ALDH1A1 | |
| SCHEMBL18182600 | 0.88 | MRGPRX4 (0.35) | MRGPRX4FABP3FABP4FABP5NPC1 | |
| SCHEMBL18532837 | 0.88 | MRGPRX4 (0.42) | MRGPRX4FABP3FABP4FABP5PTGER1 | |
| SCHEMBL18532768 | 0.86 | KDM4E (0.34) | MRGPRX4FABP3FABP4FABP5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081559-A1 | AROMATIC COMPOUND AND APPLICATION FOR SAME | Sumitomo Chemical Company, Limited (JP) | 2016-10-19 | — | — | EP | disclosed |