SCHEMBL18156464

SCHEMBL18156464

CCc1ccc(OCc2c(I)cccc2OC(C)=S)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 9/20 0.37
PPARA Q07869 5/20 0.36
FFAR1 O14842 4/20 0.35
MRGPRX4 Q96LA9 3/20 0.35
SLC22A12 Q96S37 1/20 0.34
CD274 Q9NZQ7 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18156176 0.90 FFAR4 (0.36) FFAR4PPARAFFAR1MRGPRX4SLC22A12
SCHEMBL18156465 0.89 SLC22A12 (0.41) FFAR4PPARAFFAR1MRGPRX4SLC22A12
SCHEMBL18182052 0.89 PPARA (0.37) FFAR4PPARAFFAR1MRGPRX4SLC22A12
SCHEMBL18182279 0.88 FFAR4 (0.42) FFAR4PPARAFFAR1MRGPRX4SLC22A12
SCHEMBL18182822 0.88 PPARA (0.37) FFAR4PPARAFFAR1MRGPRX4SLC22A12
SCHEMBL18156383 0.87 FFAR4 (0.38) FFAR4PPARAFFAR1MRGPRX4SLC22A12
SCHEMBL18182498 0.87 FFAR4 (0.41) FFAR4PPARAFFAR1MRGPRX4SLC22A12
SCHEMBL18182523 0.87 FFAR4 (0.38) FFAR4FFAR1MRGPRX4SLC22A12CD274
SCHEMBL18178893 0.87 MRGPRX4 (0.43) FFAR4MRGPRX4
SCHEMBL18156519 0.86 FFAR4 (0.42) FFAR4PPARAFFAR1MRGPRX4SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9573904-B2 Aromatic compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-21 US disclosed
US-20160311775-A1 AROMATIC COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-10-27 US disclosed
EP-3081559-A1 AROMATIC COMPOUND AND APPLICATION FOR SAME Sumitomo Chemical Company, Limited (JP) 2016-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160311775-A1 AROMATIC COMPOUND AND USE THEREOF ZCCHC8, CBR3, CBX8 FFAR4 2485/4885PPARA 3076/4885FFAR1 2736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.