Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 13/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813617 | 0.89 | ADORA1 (0.71) | ADORA1ADORA2AADORA2BDHODHNTRK1 | |
| SCHEMBL1813404 | 0.89 | ADORA1 (0.65) | ADORA1ADORA2AADORA2BNTRK1ADORA3 | |
| SCHEMBL1815646 | 0.83 | ADORA1 (0.56) | ADORA1ADORA2AADORA2BNTRK1ADORA3 | |
| SCHEMBL1814209 | 0.81 | ADORA1 (0.83) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL1806490 | 0.80 | ADORA1 (0.68) | ADORA1ADORA2AADORA2BDHODHADORA3 | |
| SCHEMBL1820415 | 0.79 | ADORA1 (0.73) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL3306844 | 0.79 | ADORA1 (0.53) | ADORA1ADORA2AADORA2BDHODHNTRK1 | |
| SCHEMBL1815006 | 0.78 | ADORA1 (0.72) | ADORA1ADORA2AADORA2BNTRK1ADORA3 | |
| SCHEMBL1815882 | 0.78 | ADORA1 (0.71) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL1819947 | 0.78 | ADORA1 (0.69) | ADORA1ADORA2AADORA2BDHODHADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321296-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-05-18 | — | — | EP | disclosed |
| US-20100099681-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-22 | — | — | US | disclosed |
| WO-2010020363-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099681-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | CYP3A5, ABAT, TPMT | ADORA1 724/4885ADORA2A 596/4885ADORA2B 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.