SCHEMBL18156563

SCHEMBL18156563

CC(F)(c1cc(Br)c(NC(=O)c2cccc(NC(=O)c3cccnc3Cl)c2F)c(Br)c1)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.43
HPGD P15428 2/20 0.43
HTT P42858 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KMT2A Q03164 4/20 0.42
GAA P10253 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MEN1 O00255 2/20 0.40
MDM4 O15151 1/20 0.39
MITF O75030 1/20 0.39
MDM2 Q00987 1/20 0.39
ATM Q13315 1/20 0.39
GPR35 Q9HC97 1/20 0.39
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
PTGES O14684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1767307 0.90 SMN1; SMN2 (0.44) SMN1; SMN2HPGDHTTL3MBTL1KDM4E
SCHEMBL1766766 0.88 SMN1; SMN2 (0.42) SMN1; SMN2HPGDHTTL3MBTL1KDM4E
SCHEMBL31175836 0.84 SMN1; SMN2 (0.41) SMN1; SMN2HPGDHTTL3MBTL1KDM4E
SCHEMBL1767169 0.84 SMN1; SMN2 (0.41) SMN1; SMN2HPGDHTTL3MBTL1KDM4E
SCHEMBL1767151 0.82 HPGD (0.39) SMN1; SMN2HPGDHTTL3MBTL1KDM4E
SCHEMBL1766492 0.82 SMN1; SMN2 (0.39) SMN1; SMN2HPGDHTTL3MBTL1KDM4E
SCHEMBL12348593 0.82 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTL3MBTL1KDM4E
SCHEMBL1830511 0.81 SMN1; SMN2 (0.44) SMN1; SMN2HPGDHTTL3MBTL1KDM4E
SCHEMBL12356417 0.80 HPGD (0.38) SMN1; SMN2HPGDHTTL3MBTL1KDM4E
SCHEMBL1766905 0.80 SMN1; SMN2 (0.45) SMN1; SMN2HPGDHTTL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081552-A1 PEST CONTROL AGENT CONTAINING AN AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2016-10-19 EP disclosed