Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.68 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148776 | 0.92 | MTOR (0.80) | MTOR | |
| SCHEMBL18156590 | 0.88 | MTOR (0.86) | MTORPIK3CAPIK3CG | |
| SCHEMBL2148703 | 0.87 | MTOR (0.85) | MTOR | |
| SCHEMBL17747079 | 0.87 | MTOR (0.76) | MTOR | |
| SCHEMBL18142943 | 0.87 | MTOR (0.70) | MTORPIK3CAPIK3CG | |
| SCHEMBL18142934 | 0.87 | MTOR (0.84) | MTOR | |
| SCHEMBL18142963 | 0.86 | MTOR (0.83) | MTOR | |
| SCHEMBL12463116 | 0.86 | MTOR (0.65) | MTORPIK3CAPIK3CG | |
| SCHEMBL18143009 | 0.85 | MTOR (0.84) | MTOR | |
| SCHEMBL18142939 | 0.85 | MTOR (0.84) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519102-B1 | NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS | DEV CENTER BIOTECHNOLOGY (TW) | 2016-10-19 | — | — | EP | disclosed |