Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148792 | 0.93 | MTOR (1.00) | MTOR | |
| SCHEMBL2153327 | 0.92 | MTOR (1.00) | MTOR | |
| SCHEMBL2148596 | 0.91 | MTOR (1.00) | MTOR | |
| SCHEMBL13718210 | 0.91 | MTOR (1.00) | MTOR | |
| SCHEMBL2154546 | 0.91 | MTOR (0.85) | MTOR | |
| SCHEMBL2148708 | 0.91 | MTOR (1.00) | MTOR | |
| SCHEMBL2152844 | 0.91 | MTOR (1.00) | MTOR | |
| SCHEMBL2153931 | 0.90 | MTOR (1.00) | MTOR | |
| SCHEMBL2152847 | 0.90 | MTOR (0.84) | MTOR | |
| SCHEMBL2153568 | 0.89 | MTOR (1.00) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519102-B1 | NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS | DEV CENTER BIOTECHNOLOGY (TW) | 2016-10-19 | — | — | EP | disclosed |