SCHEMBL18156595

SCHEMBL18156595

CCOc1cnc(-c2ccc(NC(=O)Nc3ccc(N4CCOCC4)cc3)cc2)nc1N1CCOCC1

nearest known ligand 0.87

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MTOR P42345 20/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153299 0.95 MTOR (0.83) MTOR
SCHEMBL13718740 0.93 MTOR (1.00) MTOR
SCHEMBL13718421 0.92 MTOR (1.00) MTOR
SCHEMBL13832735 0.92 MTOR (0.84) MTOR
SCHEMBL12463252 0.92 MTOR (1.00) MTOR
SCHEMBL2153782 0.92 MTOR (1.00) MTOR
Hydrochloric Acid SCHEMBL13718504 0.92 MTOR (0.98) MTOR
SCHEMBL2170127 0.91 MTOR (1.00) MTOR
SCHEMBL2170698 0.90 MTOR (1.00) MTOR
SCHEMBL2148792 0.90 MTOR (1.00) MTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2519102-B1 NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS DEV CENTER BIOTECHNOLOGY (TW) 2016-10-19 EP disclosed