SCHEMBL18156643

SCHEMBL18156643

CCCC1CCC(c2ccc(-c3cc(F)cc(F)c3)cc2)OC1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.48
DGAT1 O75907 1/20 0.34
CHRM2 P08172 1/20 0.33
CYP2C9 P11712 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17552982 0.91 FASN (0.48) FASNDGAT1CHRM2CYP2C9ALDH1A1
SCHEMBL10550528 0.91 FASN (0.48) FASNDGAT1CHRM2CYP2C9ALDH1A1
SCHEMBL18156625 0.89 FASN (0.39) FASNDGAT1CHRM2SLC6A4SLC6A3
SCHEMBL14621251 0.88 FASN (0.48) FASNDGAT1CHRM2CYP2C9ALDH1A1
SCHEMBL15744345 0.87 FASN (0.47) FASNDGAT1CHRM2CYP2C9
SCHEMBL16591211 0.86 FASN (0.51) FASNDGAT1CHRM2CYP2C9ALDH1A1
SCHEMBL12930554 0.86 FASN (0.51) FASNDGAT1CHRM2CYP2C9ALDH1A1
SCHEMBL10555297 0.86 FASN (0.43) FASNCYP2C9ALDH1A1LMNAMAPT
SCHEMBL30332320 0.86 FASN (0.37) FASNCYP2C9
SCHEMBL18418532 0.85 FASN (0.46) FASNDGAT1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081621-B1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR SAMSUNG DISPLAY CO LTD (KR) 2019-06-12 EP disclosed
US-20170349831-A1 LIQUID CRYSTAL COMPOUND CONTAINING DIFLUORMETHOXY BRIDGE, COMPOSITION AND APPLICATION THEREOF BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2017-12-07 US disclosed
US-20170349831-A1 LIQUID CRYSTAL COMPOUND CONTAINING DIFLUORMETHOXY BRIDGE, COMPOSITION AND APPLICATION THEREOF BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2017-12-07 US disclosed
US-9783735-B2 Liquid crystal display device and liquid crystal composition used therefor SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-10 US disclosed
US-9783735-B2 Liquid crystal display device and liquid crystal composition used therefor SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-10 US disclosed
EP-3222696-A2 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR Samsung Display Co., Ltd. (KR) 2017-09-27 EP disclosed
US-20160304783-A1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR DONGJIN SEMICHEM CO., LTD. (KR) 2016-10-20 US disclosed
US-20160304783-A1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR DONGJIN SEMICHEM CO., LTD. (KR) 2016-10-20 US disclosed
EP-3081621-A2 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR Samsung Display Co., Ltd. (KR) 2016-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304783-A1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR SLC39A11, CYP4F11, WEE1 FASN 2164/4885DGAT1 1761/4885CHRM2 1835/4885
US-20170349831-A1 LIQUID CRYSTAL COMPOUND CONTAINING DIFLUORMETHOXY BRIDGE, COMPOSITION AND APPLICATION THEREOF PLD1, CCND1, LPCAT1 FASN 1358/4885DGAT1 283/4885CHRM2 1179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.