SCHEMBL18159155

SCHEMBL18159155

CC1[C@H](O[C@@H]2C[C@@](OC=O)(O[C@@H]3C(O)[C@H](O[C@@H]4C(CO)O[C@@H](OC(C)(C)C)C(O)[C@H]4O)OC(CO)[C@@H]3O)OC([C@H](O)[C@H](O)CO)[C@@H]2C)OC(CO)[C@H](O)[C@@H]1O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 6/20 0.37
▸ MAG P20916 6/20 0.37
▸ SELE P16581 5/20 0.35
▸ SELL P14151 1/20 0.33
▸ SELP P16109 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18165663 0.91 MAG (0.40) SIGLEC7MAGSELESELLSELP
SCHEMBL18160012 0.91 MAG (0.40) SIGLEC7MAGSELESELLSELP
SCHEMBL18159157 0.87 SIGLEC7 (0.39) SIGLEC7MAGSELESELLSELP
SCHEMBL18159154 0.83 SIGLEC7 (0.52) SIGLEC7MAGSELESELLSELP
SCHEMBL13059905 0.82 SIGLEC7 (0.41) SIGLEC7MAGSELESELLSELP
SCHEMBL13059894 0.80 MAG (0.38) SIGLEC7MAGSELESELLSELP
SCHEMBL18159145 0.79 SELL (0.51) SIGLEC7MAGSELESELLSELP
SCHEMBL18165655 0.78 SIGLEC7 (0.39) SIGLEC7MAGSELESELLSELP
SCHEMBL18160016 0.78 SIGLEC7 (0.39) SIGLEC7MAGSELESELLSELP
SCHEMBL18165661 0.78 SIGLEC7 (0.43) SIGLEC7MAGSELESELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160304858-A1 DIRECTED EVOLUTION OF MULTIVALENT GLYCOPEPTIDES THAT TIGHTLY BIND TO TARGET PROTEINS BRANDEIS UNIVERSITY 2016-10-20 — — US disclosed
US-20160304628-A1 MULTIVALENT GLYCOPEPTIDES THAT TIGHTLY BIND TO TARGET PROTEINS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304628-A1 MULTIVALENT GLYCOPEPTIDES THAT TIGHTLY BIND TO TARGET PROTEINS SIGLEC7, SIGLEC9, STT3A SIGLEC7 1/4885MAG 288/4885SELE 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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