⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195973 | 0.64 | — | — | |
| SCHEMBL5264837 | 0.64 | — | — | |
| SCHEMBL10412748 | 0.64 | — | — | |
| SCHEMBL7494932 | 0.64 | — | — | |
| SCHEMBL5730138 | 0.64 | — | — | |
| SCHEMBL2395955 | 0.64 | — | — | |
| SCHEMBL1266039 | 0.62 | — | — | |
| SCHEMBL10825464 | 0.62 | — | — | |
| SCHEMBL1766413 | 0.60 | — | — | |
| SCHEMBL1767178 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10858357-B2 | Water-soluble myosin 2 inhibitors for the treatment of neurological, neuropathic or psychiatric diseases | PARIS SCIENCES ET LETTRES-QUARTIER LATIN (FR) | 2020-12-08 | — | — | US | claimed |
| EP-3529249-A1 | WATER-SOLUBLE MYOSIN 2 INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL, NEUROPATHIC OR PSYCHIATRIC DISEASES | Paris Sciences et Lettres - Quartier Latin (FR) | 2019-08-28 | — | — | EP | claimed |
| EP-3490985-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2019-06-05 | — | — | EP | claimed |
| US-20190084979-A1 | WATER-SOLUBLE MYOSIN 2 INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL, NEUROPATHIC OR PSYCHIATRIC DISEASES | PARIS SCIENCES ET LETTRES (FR) | 2019-03-21 | — | — | US | claimed |
| CN-109476647-A | The pyrimidine compound of weeding | 巴斯夫欧洲公司 | 2019-03-15 | — | — | CN | claimed |
| WO-2018019555-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2018-02-01 | — | — | WO | claimed |
| WO-2017129782-A1 | WATER-SOLUBLE MYOSIN 2 INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL, NEUROPATHIC OR PSYCHIATRIC DISEASES | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2017-08-03 | — | — | WO | claimed |
| US-8203011-B2 | 3′,4′,5-trimethoxy flavone derivatives as stimulant of mucus secretion, method for the same, and pharmaceutical composition comprising the same | DONG-A PHARM. CO., LTD. (KR) | 2012-06-19 | — | — | US | claimed |
| EP-2170857-B1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULANT OF MUCUS SECRETION, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG A PHARM CO LTD (KR) | 2011-10-19 | — | — | EP | claimed |
| US-20100130448-A1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULATN OF MUCUS SECRETION, METHOD FOR THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG-A PHARM. CO., LTD (KR) | 2010-05-27 | — | — | US | claimed |
| WO-2000069833-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL URACILS AS ANTICOAGULATIVE AGENTS | PHARMACIA CORPORATION (US) | 2000-11-23 | — | — | WO | claimed |
| WO-1996028444-A1 | 5,10-DIHYDROPYRIMIDO[4,5-b]QUINOLIN-4(1H)-ONE TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1996-09-19 | — | — | WO | claimed |
| CN-1021191-C | SUBSTITUTED 3-(4-NITROPHENOXY) PYRAZOLES HERBICIDES COMPOSITION | MONSANTO CO (US) | 1993-06-16 | — | — | CN | claimed |
| US-4916128-A | Thiadiazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | claimed |
| EP-0341990-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-11-15 | — | — | EP | claimed |
| EP-0135088-B1 | 7-Amino-3[1-pyridiniomethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-en-2-carboxylates, process for their preparation and their use as intermediates in the synthesis of beta-lactam antibiotics | BAYER AG (DE) | 1989-10-04 | — | — | EP | claimed |
| EP-0102740-B1 | N-FORMYL AND N-HYDROXYMETHYL-3-PHENOXY-1-AZETIDINECARBOXAMIDES AND THEIR PREPARATION AND USE | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-11-05 | — | — | EP | claimed |
| EP-0066989-B1 | NOVEL SUBSTITUTED NITRODIPHENYL ETHERS, HERBICIDAL COMPOSITIONS CONTAINING THEM, A PROCESS FOR THE PREPARATION OF THE NITRODIPHENYL ETHERS AND THE USE THEREOF FOR COMBATING WEEDS | ROHM AND HAAS COMPANY (US) | 1985-03-20 | — | — | EP | claimed |
| EP-0066989-A2 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, a process for the preparation of the nitrodiphenyl ethers and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1982-12-15 | — | — | EP | claimed |
| US-4021542-A | Derivatives of hydrazino-monosaccharides and aldohexoses which are useful as intermediates for preparing compounds or as compounds which lower the uric acid | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1977-05-03 | — | — | US | claimed |