Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060809 | 0.81 | CYP4F2 (0.50) | MAPK1KDM4ECYP4F2CYP4A11KMT2A | |
| SCHEMBL1808773 | 0.81 | CYP2C19 (0.44) | CYP4F2CYP4A11KMT2AMEN1ALDH1A1 | |
| SCHEMBL11387146 | 0.80 | CYP4F2 (0.49) | MAPK1KDM4ECYP4F2CYP4A11KMT2A | |
| SCHEMBL5973349 | 0.80 | CYP4F2 (0.41) | MAPK1KDM4ECYP4F2CYP4A11KMT2A | |
| SCHEMBL11345271 | 0.80 | CYP4F2 (0.49) | MAPK1CYP4F2CYP4A11KMT2AMAPT | |
| SCHEMBL1633342 | 0.79 | SMN1; SMN2 (0.41) | MAPK1KDM4ECYP4F2CYP4A11KMT2A | |
| SCHEMBL17454 | 0.79 | SMN1; SMN2 (0.40) | MAPK1KDM4ECYP4F2CYP4A11KMT2A | |
| SCHEMBL8311121 | 0.79 | CYP4F2 (0.44) | MAPK1KDM4ECYP4F2CYP4A11KMT2A | |
| SCHEMBL21399965 | 0.79 | CYP4F2 (0.47) | MAPK1CYP4F2CYP4A11KMT2AMAPT | |
| SCHEMBL29210884 | 0.78 | CYP4F2 (0.46) | MAPK1KDM4ECYP4F2CYP4A11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061590-A1 | NOVEL CARBOXAMIDE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2011-05-26 | — | — | WO | disclosed |
| WO-2011061590-A1 | NOVEL CARBOXAMIDE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2011-05-26 | — | — | WO | disclosed |