Aloin

Aloin

SCHEMBL181616

O=C1c2c(O)cccc2[C@@H]([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2cc(CO)cc(O)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 9/20 1.00
KDM4E B2RXH2 2/20 0.68
MAPT P10636 2/20 0.68
USP2 O75604 4/20 0.52
HKDC1 Q2TB90 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
TNNI3 P19429 2/20 0.52
TNNT2 P45379 2/20 0.52
TNNC1 P63316 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
LMNA P02545 1/20 0.52
GLA P06280 1/20 0.52
CYP3A4 P08684 1/20 0.52
THRB P10828 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aloin SCHEMBL29626884 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1
Aloin SCHEMBL29832551 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1
Aloin SCHEMBL4974135 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1
Aloin SCHEMBL14837252 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1
Aloin SCHEMBL12978352 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1
Aloin SCHEMBL14837254 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1
Aloin SCHEMBL14003222 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1
Aloin SCHEMBL12978350 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1
Aloin SCHEMBL14278534 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1
Aloin SCHEMBL13990758 1.00 EPHX2 (1.00) EPHX2KDM4EMAPTUSP2HKDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5977 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075559-A Portulaca oleracea extract based on bioaffinity ultrafiltration screening and preparation method and application thereof 2026-05-26 CN claimed
CN-122056966-A Multifunctional aloe fermentation product and preparation method and application thereof 山东省科学院生物研究所 2026-05-19 CN claimed
CN-122017224-A Method for screening antibacterial compounds by high-flux targeted phytophthora elicitin based on DHE fluorescence intensity and application 南京农业大学三亚研究院 2026-05-12 CN claimed
US-20260096569-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES APEEL TECH INC (US) 2026-04-09 US claimed
EP-4680027-A1 A METHOD FOR IMPARTING ANTIMICROBIAL PROPERTIES TO A SYNTHETIC SUBSTRATE Biocompatibility Innovation Srl (IT) 2026-01-21 EP claimed
US-12509789-B2 Sulfonate electroplating bath, process for refining metal by electrolytic depositing and process for controlling metal morphology in electrolytic refining BASF SE (DE) 2025-12-30 US claimed
WO-2025262717-A1 AN IMPROVED CLEANING COMPOSITION FOR THE REMOVAL OF OIL, RUST, AND CARBON CHHABRA PRAVEEN (IN) 2025-12-26 WO claimed
EP-4108265-B1 FUNCTIONALIZED BIOLOGICAL MATRIX MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF VENUS MEDTECH HANGZHOU INC (CN) 2025-09-03 EP claimed
US-12403218-B2 Biological valve material, preparation method, and cross-linking agent CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUTE OF BIOMEDICAL ENGINEERING (CN) 2025-09-02 US claimed
US-20250271426-A1 REDUCTION OF BITTER TASTE OF ACTIVE PHARMACEUTICAL INGREDIENTS AND RELATED ASSAYS AND SCREENING METHODS FIRMENICH INCORPORATED (US) 2025-08-28 US claimed
EP-0621787-A1 SKIN THERAPEUTIC MIXTURE CONTAINING COLD-PROCESSED ALOE VERA EXTRACT, WITH YELLOW SAP AND ALOIN REMOVED ROYALE RENAISSANCE INC. (US) 1994-11-02 EP claimed
US-5356811-A Method of processing stabilized aloe vera gel obtained from the whole aloe vera leaf COATS BILLY C (US) 1994-10-18 US claimed
US-5266318-A Synergistic wound healing mixture with allantoin ROYALE RENAISSANCE, INC. (US) 1993-11-30 US claimed
WO-1993011780-A1 SKIN THERAPEUTIC MIXTURE CONTAINING COLD-PROCESSED ALOE VERA EXTRACT, WITH YELLOW SAP AND ALOIN REMOVED ROYALE RENAISSANCE, INC. (US) 1993-06-24 WO claimed
EP-0374890-A1 Process for the production of anthraquinone derivatives GERUM ESTABLISHMENT (LI) 1990-06-27 EP claimed
US-4656029-A Cosmetic composition containing aloesin as an agent for protection against sunlight and its use for skin and hair protection L'OREAL (FR) 1987-04-07 US claimed
US-4591387-A Aloe vera leaf processor GRAY WILLIAM G DE 1986-05-27 US claimed
US-4555987-A Method and apparatus for extraction of aloe vera gel TUMLINSON LARRY N 1985-12-03 US claimed
US-4481185-A Stable emulsions obtained from a natural emulsifier stabilized with aloes juice SOCIETE ANONYME DITE: L'OREAL (FR) 1984-11-06 US claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed