SCHEMBL18165

SCHEMBL18165

NC1CCOCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2771972 1.00 TTR (0.36)
SCHEMBL9051405 1.00 TTR (0.36)
Methane SCHEMBL12477494 0.96
Hydrochloric Acid SCHEMBL1434836 0.96 TTR (0.33)
SCHEMBL14841784 0.96
Hydrochloric Acid SCHEMBL4491180 0.96 TTR (0.33)
Iodide SCHEMBL3075479 0.96
SCHEMBL9760083 0.96 TTR (0.33)
Bromide SCHEMBL5069293 0.96
Hydrochloric Acid SCHEMBL17919 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8587 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036730-A Gαq/11 protein inhibitor with purine skeleton, and preparation method and application thereof 中山大学 2026-05-15 CN claimed
CN-122010986-A Preparation method of near infrared luminous halide monocrystal scintillator 北京工业大学 2026-05-12 CN claimed
US-20260109691-A1 PROCESS FOR MANUFACTURING ALOGABAT HOFFMANN-LA ROCHE INC. (US) 2026-04-23 US claimed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
CN-120092001-A Method for producing ALOGABAT 豪夫迈·罗氏有限公司 2025-06-03 CN claimed
US-20250154198-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2025-05-15 US claimed
CN-119735600-A 3-Ureido substituted thieno [2,3-b ] pyridine compound and preparation method and application thereof 华东师范大学 2025-04-01 CN claimed
CN-119661508-A Preparation method and application of dual-mechanism ERK inhibitor 苏州健雄职业技术学院 2025-03-21 CN claimed
US-20250092026-A1 METHOD FOR PREPARING BENZOFURAN DERIVATIVE JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2025-03-20 US claimed
CN-114761404-B Substituted bicyclic heteroaryl compounds 百时美施贵宝公司 2025-02-21 CN claimed
WO-2003027102-A1 3-(ARYLAMINO)METHYLENE-1, 3-DIHYDRO-2H-INDOL-2-ONES AS KINASE INHIBITORS ALLERGAN, INC. (US) 2003-04-03 WO claimed
US-20030004359-A1 Processes for producing tetrahydropyranyl-4-sulfonates and 4-aminotetrahydropyran compound UBE INDUSTRIES, LTD. (JP) 2003-01-02 US claimed
WO-2002098850-A2 CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2002-12-12 WO claimed
US-20020188018-A1 3-indolyl-4-phenyl-1H-pyrrole-2,5-dione derivatives as inhibitors of glycogen synthase kinase-3beta GONG LEYI (US) 2002-12-12 US claimed
US-6479490-B2 TREATMENT OF DISEASES CHARACTERIZED BY EXCESS TH2 CYTOKINES AND/ OR AN EXCESS IGE PRODUCTION. SYNTEX (U.S.A.) LLC 2002-11-12 US claimed
EP-1247807-A1 PROCESSES FOR PRODUCING TETRAHYDROPYRANYL-4-SULFONATE AND 4-AMINOTETRAHYDROPYRAN COMPOUND Ube Industries, Ltd. (JP) 2002-10-09 EP claimed
WO-2002036555-A1 SULFAMIDES AS GAMMA-SECRETASE INHIBITORS MERCK SHARP & DOHME LIMITED (GB) 2002-05-10 WO claimed
US-20020052397-A1 3-indolyl-4-phenyl-1H-pyrrole-2,5-dione derivatives as inhibitors of glycogen synthase kinase-3beta SYNTEX (U.S.A.) LLC 2002-05-02 US claimed
WO-2001070232-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2001-09-27 WO claimed
US-5821240-A ENZYME INHIBITORS, SIGNAL INHIBITORS FOR ANTIINFLAMMATORY AGENTS, ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS AND HORMONE INHIBITORS DR. KARL THOMAE GMBH (DE) 1998-10-13 US claimed