Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.73 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.66 |
| ▸ | LDHB | P07195 | 4/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.38 |
| ▸ | TERF2 | Q15554 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 3/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360076 | 1.00 | KDM1A (0.73) | KDM1ARCOR1LDHBKEAP1TERF2 | |
| Polymyxin B Nonapeptide SCHEMBL20108926 | 0.93 | KDM1A (0.77) | KDM1ARCOR1LDHBKEAP1TERF2 | |
| Polymyxin B Nonapeptide SCHEMBL21498184 | 0.93 | KDM1A (0.77) | KDM1ARCOR1LDHBKEAP1TERF2 | |
| Polymyxin B Nonapeptide SCHEMBL19386845 | 0.93 | KDM1A (0.77) | KDM1ARCOR1LDHBKEAP1TERF2 | |
| Polymyxin B Nonapeptide SCHEMBL29358904 | 0.93 | KDM1A (0.77) | KDM1ARCOR1LDHBKEAP1TERF2 | |
| Polymyxin B Nonapeptide SCHEMBL17882149 | 0.93 | KDM1A (0.77) | KDM1ARCOR1LDHBKEAP1TERF2 | |
| Polymyxin B Nonapeptide SCHEMBL25547777 | 0.93 | KDM1A (0.77) | KDM1ARCOR1LDHBKEAP1TERF2 | |
| SCHEMBL25455162 | 0.91 | KDM1A (0.67) | KDM1ARCOR1LDHBKEAP1TERF2 | |
| SCHEMBL21504107 | 0.90 | KDM1A (0.77) | KDM1ARCOR1LDHBKEAP1TERF2 | |
| SCHEMBL21504370 | 0.89 | KDM1A (0.67) | KDM1ARCOR1LDHBKEAP1TERF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016166103-A1 | POLYMYXIN DERIVATIVES | XELLIA PHARMACEUTICALS APS (DK) | 2016-10-20 | — | — | WO | disclosed |