⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14436603 | 0.81 | MAPT (0.38) | — | |
| SCHEMBL19429643 | 0.79 | MAPT (0.41) | — | |
| SCHEMBL14447243 | 0.79 | MAPT (0.37) | — | |
| SCHEMBL12754949 | 0.77 | MAPT (0.46) | — | |
| SCHEMBL19403808 | 0.76 | POLB (0.42) | — | |
| SCHEMBL17179142 | 0.72 | — | — | |
| SCHEMBL843842 | 0.71 | MAPT (0.61) | — | |
| SCHEMBL843843 | 0.71 | MAPT (0.61) | — | |
| SCHEMBL9925432 | 0.71 | MAPT (0.61) | — | |
| SCHEMBL7030472 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9347066-B2 | Plants and seeds with altered storage compound levels, related constructs and methods involving genes encoding proteins with similarity to bacterial 2,4-dihydroxy-hept-2-ene-1,7-dioic acid class II-like aldolase proteins | CORTEVA AGRISCIENCE LLC | 2016-05-24 | — | — | US | disclosed |
| US-20130111633-A1 | PLANTS AND SEEDS WITH ALTERED STORAGE COMPOUND LEVELS, RELATED CONSTRUCTS AND METHODS INVOLVING GENES ENCODING PROTEINS WITH SIMILARITY TO BACTERIAL 2,4-DIHYDROXY-HEPT-2-ENE-1,7-DIOIC ACID CLASS II-LIKE ALDOLASE PROTEINS | E.I. DU PONT DE NEMOOURS AND COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| EP-2494043-A2 | PLANTS AND SEEDS WITH ALTERED STORAGE COMPOUND LEVELS, RELATED CONSTRUCTS AND METHODS INVOLVING GENES ENCODING PROTEINS WITH SIMILARITY TO BACTERIAL 2,4-DIHYDROXY-HEPT-2-ENE-1,7-DIOIC ACID CLASS II-LIKE ALDOLASE PROTEINS | E. I. du Pont de Nemours and Company (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011053898-A2 | PLANTS AND SEEDS WITH ALTERED STORAGE COMPOUND LEVELS, RELATED CONSTRUCTS AND METHODS INVOLVING GENES ENCODING PROTEINS WITH SIMILARITY TO BACTERIAL 2,4-DIHYDROXY-HEPT-2-ENE-1,7-DIOIC ACID CLASS II-LIKE ALDOLASE PROTEINS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-05 | — | — | WO | disclosed |