Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | REN | P00797 | 3/20 | 0.50 |
| ▸ | GNPAT | O15228 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18173547 | 1.00 | MME (0.53) | MMELTA4HRENGNPATMMP2 | |
| SCHEMBL29365781 | 1.00 | MME (0.53) | MMELTA4HRENGNPATMMP2 | |
| SCHEMBL10423770 | 0.92 | BACE1 (0.53) | BACE1 | |
| SCHEMBL10423767 | 0.92 | BACE1 (0.53) | BACE1 | |
| SCHEMBL2519489 | 0.90 | ACE (0.56) | MMERENMMP2MMP7MMP9 | |
| SCHEMBL2519495 | 0.90 | ACE (0.56) | MMERENMMP2MMP7MMP9 | |
| SCHEMBL29896984 | 0.89 | MME (0.52) | MMERENGNPATACEOPRD1 | |
| SCHEMBL31607204 | 0.89 | MME (0.55) | MMEGNPATMMP2MMP7MMP9 | |
| SCHEMBL8060317 | 0.88 | MME (0.59) | MMELTA4HRENMMP2MMP7 | |
| SCHEMBL8060325 | 0.88 | MME (0.59) | MMELTA4HRENMMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395521-A1 | MICROBIOME REGULATORS AND RELATED USES THEREOF | KALEIDO BIOSCIENCES, INC. (US) | 2022-12-15 | — | — | US | disclosed |
| US-20180296582-A1 | MICROBIOME REGULATORS AND RELATED USES THEREOF | HERCULES CAPITAL, INC. | 2018-10-18 | — | — | US | disclosed |
| EP-3285778-A2 | MICROBIOME REGULATORS AND RELATED USES THEREOF | Kaleido Biosciences, Inc. (US) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016172658-A2 | MICROBIOME REGULATORS AND RELATED USES THEREOF | KALEIDO BIOSCIENCES, INC. (US) | 2016-10-27 | — | — | WO | disclosed |