Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL18173948 | 0.91 | CYP1A2 (0.47) | CYP1A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28252667 | 0.89 | CYP1A2 (0.46) | CYP1A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27867710 | 0.84 | CYP1A2 (0.39) | CYP1A2ALDH1A1 | |
| SCHEMBL8329095 | 0.83 | — | — | |
| SCHEMBL8328456 | 0.83 | — | — | |
| SCHEMBL2662411 | 0.83 | — | — | |
| Bromide SCHEMBL11542091 | 0.81 | CYP1A2 (0.55) | CYP1A2KMT2A | |
| Iodide SCHEMBL4422616 | 0.81 | CYP1A2 (0.55) | CYP1A2KMT2A | |
| SCHEMBL12932566 | 0.81 | CYP1A2 (0.61) | CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL27337129 | 0.81 | CYP1A2 (0.55) | CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286163-A1 | METHOD FOR PREPARING STRUCTURED DIRECTING AGENT | Johnson Matthey Public Limited Company (GB) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016172128-A1 | METHOD FOR PREPARING STRUCTURED DIRECTING AGENT | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2016-10-27 | — | — | WO | disclosed |