SCHEMBL18174595

SCHEMBL18174595

Cc1ccnc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cc(C)ccn5)cc4)c4cc(-c5ccc6ccccc6c5)ccc34)cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.41
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
CCR8 P51685 1/20 0.41
DCTPP1 Q9H773 1/20 0.39
CTRC Q99895 1/20 0.39
HTR2B P41595 1/20 0.38
HTR5A P47898 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP17A1 P05093 1/20 0.37
CYP19A1 P11511 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 3/20 0.37
LMNA P02545 3/20 0.37
MAPT P10636 2/20 0.37
GLA P06280 1/20 0.37
TSHR P16473 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977444 0.96 CYP2A6 (0.40) CYP2A6CCR1CCR5CCR8DCTPP1
SCHEMBL15977441 0.93 CYP2A6 (0.42) CYP2A6CCR1CCR5CCR8DCTPP1
SCHEMBL10032638 0.93 CCR1 (0.44) CYP2A6CCR1CCR5CCR8DCTPP1
SCHEMBL10032756 0.92 CYP2A6 (0.43) CYP2A6CCR1CCR5CCR8DCTPP1
SCHEMBL10032684 0.88 CYP2A6 (0.46) CYP2A6CCR1CCR5CCR8TDP1
SCHEMBL15160984 0.88 CYP2A6 (0.48) CYP2A6CCR1CCR5CCR8ALDH1A1
SCHEMBL15977629 0.88 CYP2A6 (0.48) CYP2A6CCR1CCR5CCR8ALDH1A1
SCHEMBL10032753 0.87 CYP2A6 (0.44) CYP2A6CCR1CCR5CCR8CTRC
SCHEMBL18174555 0.86 CCR1 (0.55) CYP2A6CCR1CCR5CCR8ALDH1A1
SCHEMBL18174592 0.85 CYP2A6 (0.46) CYP2A6CCR1CCR5CCR8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed