SCHEMBL18174598

SCHEMBL18174598

Cc1cc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccnc(C)c5)cc4)c4cc(-c5cccc(-c6ccccc6)c5)ccc34)cc2)ccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.46
PSEN1 P49768 2/20 0.45
PSEN2 P49810 2/20 0.45
APH1B Q8WW43 2/20 0.45
NCSTN Q92542 2/20 0.45
APH1A Q96BI3 2/20 0.45
PSENEN Q9NZ42 2/20 0.45
WNT3A P56704 7/20 0.45
PORCN Q9H237 1/20 0.45
MAP4K4 O95819 2/20 0.43
LRRK2 Q5S007 1/20 0.43
PIK3CA P42336 1/20 0.41
CDC7 O00311 1/20 0.40
ROCK2 O75116 1/20 0.40
CDK2 P24941 1/20 0.40
GSK3B P49841 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
IRAK4 Q9NWZ3 1/20 0.40
CLK1 P49759 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174636 0.97 DYRK1A (0.46) DYRK1APSEN1PSEN2APH1BNCSTN
SCHEMBL15160923 0.97 PSEN1 (0.48) DYRK1APSEN1PSEN2APH1BNCSTN
SCHEMBL15160926 0.97 DYRK1A (0.49) DYRK1APSEN1PSEN2APH1BNCSTN
SCHEMBL15977481 0.97 DYRK1A (0.49) DYRK1APSEN1PSEN2APH1BNCSTN
SCHEMBL10300986 0.95 MAP4K4 (0.47) DYRK1APSEN1PSEN2APH1BNCSTN
SCHEMBL18174738 0.92 DYRK1A (0.50) DYRK1APSEN1PSEN2APH1BNCSTN
SCHEMBL16189065 0.89 DYRK1A (0.56) DYRK1APSEN1PSEN2APH1BNCSTN
SCHEMBL15160979 0.88 PSEN1 (0.50) DYRK1APSEN1PSEN2APH1BNCSTN
SCHEMBL15161099 0.88 DYRK1A (0.46) DYRK1APSEN1PSEN2APH1BNCSTN
SCHEMBL10032662 0.87 DYRK1A (0.45) DYRK1APSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed